The No. 10 Notre Dame Fighting Irish (5-1) carry the 24th-ranked scoring offense in the country into a clash with the No. 25 Louisville Cardinals (5-0), with the No. 23 scoring defense, on Saturday, October 7, 2023. The Fighting Irish are 6.5-point favorites. The over/under is 53.5 in the contest.

You will take a look at odds, spreads, over/unders and more across multiple sportsbooks for the Notre Dame vs. Louisville matchup in this article.

Notre Dame vs. Louisville Game Info

  • Date: Saturday, October 7, 2023
  • Time: 7:30 PM ET
  • Channel: ABC
  • Live Stream: Watch this game on Fubo
  • City: Louisville, Kentucky
  • Venue: L&N Federal Credit Union Stadium

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Sportsbook Promo Codes

Notre Dame vs. Louisville Odds, Spread, Over/Under

Take a look at the odds, spread and over/under for this matchup at individual sportsbooks.

Favorite Total Notre Dame Moneyline Louisville Moneyline
BetMGM Notre Dame (-6.5) 53.5 -250 +200 Bet on this game with BetMGM
FanDuel Notre Dame (-6.5) 53.5 -245 +198 Bet on this game with FanDuel

Week 6 Odds

Notre Dame vs. Louisville Betting Trends

  • Notre Dame is 4-1-1 ATS this season.
  • The Fighting Irish have been favored by 6.5 points or more four times this season, and covered the spread in three of those matchups.
  • Louisville has a record of 2-2-1 against the spread this season.

Notre Dame & Louisville 2023 Futures Odds

Notre Dame
To Win the National Champ. +4000 Bet $100 to win $4000
Louisville
To Win the National Champ. +30000 Bet $100 to win $30000
To Win the ACC +750 Bet $100 to win $750

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